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KMID : 0613820140240060655
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Journal of Life Science
2014 Volume.24 No. 6 p.655 ~ p.663
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A Comparison of Components and Biological Activities Between the Hot Water Extracts of Achyranthes japonica Nakai and Achyranthes bidentata Blume
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Lee Ye-Seul
Kim Mi-Sun
Kwon Ha-Young
Sohn Ho-Yong
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Abstract
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Woosul (Achyranthis radix), a widely used material in food and oriental medicinal industry, has different origins of plant species in Korea, Japan and China. In Korea, woosul is designated as the radix of Achyranthes japonica Nakai (AJN) and Achyranthes bidentata Blume (ABB) in the regulation of The Korean Pharmacopoeia. However, the comparative study of hot water (HW) extracts between AJN and ABB is still rudimentary. In this study, HW extracts and its subsequent organic solvent fractions of AJB and ABB were prepared, and their in-vitro antimicrobial, antioxidant and anti-diabetes activities were evaluated. The HW extract of ABB has higher sugars and polyphenol compounds, and higher lightness and lower yellowness compared than those of AJN. Analysis of biological activities showed that the ethylacetate (EA) fraction of AJN and n-hexane fraction of ABB have antibacterial activities, and the EA fractions of AJN and ABB has strong antioxidation activities determined by radical scavenging activity and reducing power. In anti-diabetes activity assay, the EA fractions of AJN and ABB showed α-amylase inhibitory activities, while the butanol fractions of AJN and ABB showed α-glucosidase inhibitory activities. Our results suggest that the HW extracts of AJB and ABB have different components and extraction yields, and their subsequent fractions have different biological activity. Therefore it was concluded that the EA fraction of AJN is appropriate to develop as natural medicine, and the HW extract of AJN is suitable to woosul-tea or woosul-sikhye production.
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KEYWORD
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Achyranthes bidentata Blume, Achyranthes japonica Nakai, bioactivity, hot-water extract
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